Table 2. Comparison of cell-cycle regulated genes between T. brucei and other eukaryotes.

	T. brucei regulated	T. brucei non-reg	sum
Human regulated	20 (6)	92 (106)	112
Human non-reg	110 (124)	2136 (2122)	2246
Human, sum	130	2228	2358
S. cerevisiae regulated	39 (19)	291 (311)	330
S. cerevisiae non-reg	120 (140)	2376 (2356)	2496
S. cerevisiae , sum	159	2667	2826

Putative orthologues of T. brucei genes in yeast and human were identified by one-way BLAST searches (score >50). Cell cycle regulated or non-regulated T. brucei transcripts were further classified according to whether their orthologues in each organism were marked as being periodically expressed in Cyclebase [24] and the numbers of genes in each category are given. In brackets is the number expected in each category by chance.