Table 2. Comparison of cell-cycle regulated genes between T. brucei and other eukaryotes.
T. brucei regulated | T. brucei non-reg | sum | |
Human regulated | 20 (6) | 92 (106) | 112 |
Human non-reg | 110 (124) | 2136 (2122) | 2246 |
Human, sum | 130 | 2228 | 2358 |
S. cerevisiae regulated | 39 (19) | 291 (311) | 330 |
S. cerevisiae non-reg | 120 (140) | 2376 (2356) | 2496 |
S. cerevisiae , sum | 159 | 2667 | 2826 |
Putative orthologues of T. brucei genes in yeast and human were identified by one-way BLAST searches (score >50). Cell cycle regulated or non-regulated T. brucei transcripts were further classified according to whether their orthologues in each organism were marked as being periodically expressed in Cyclebase [24] and the numbers of genes in each category are given. In brackets is the number expected in each category by chance.