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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Anal Chem. 2011 Mar 3;83(7):2547–2553. doi: 10.1021/ac102826k

Figure 3.

Figure 3

Fluorigenic determination of the expression of the folate receptor in cancer cells using an anti-folate-receptor antibody–Protein G-PNC conjugate at pH 7.0. a) Lung carcinoma cells (A-549) that overexpress the folate receptor on their surface effectively oxidized ampliflu, due to the interaction between the anti-folate-receptor antibody–Protein G-PNC conjugate and the folate receptor. b) MCF-7 breast carcinoma cells, lacking the folate receptor, showed minimal fluorescence due to the absence of any interaction with the nanoceria conjugate