Table 1.
Boltzmann parameters
| Preparation | V j,0 (mV) | g j,min | z | n |
|---|---|---|---|---|
| Cx43-tag/Cx43-tag | −67.0/69.7 (2.5/3.3) | 0.35/0.32 (0.02/0.03) | −1.15/1.12 (0.09/0.10) | 10 |
| wt-Cx43/wt-Cx43a | −60.8/62.9 (0.6/0.4) | 0.26/0.25 (0.01/0.01) | −3.4/2.9 (0.23/0.13) | 11 |
| wt-Cx43/Cx43-tag | −72.5/70.9 (2.9/2.1) | 0.23/0.30 (0.02/0.02) | −1.3/2.1 (0.07/0.16) | 15 |
| Cx40-tag/Cx40-tag | −46.5/47.5 (1.3/1.3) | 0.24/0.20 (0.02/0.02) | −3.3/3.8 (0.51/0.48) | 4 |
| wt-Cx40/wt-Cx40b | −55.1/55.9 (1.6/1.1) | 0.20/0.19 (0.02/0.01) | −1.82/2.3 (0.18/0.20) | 13 |
| wt-Cx40/Cx40-tag | −124.5/10.2 (11.3/2.1) | n.d./0.07 (–/0.01) | −0.33/1.8 (0.01/0.18) | 5 |
| Cx45-tag/Cx45-tag | −43.4/47.0 (0.8/1.2) | 0.15/0.12 (0.01/0.02) | −2.2/1.8 (0.13/0.13) | 9 |
| wt-Cx45/wt-Cx45a | −38.9/38.5 (0.7/0.7) | 0.17/0.16 (0.01/0.01) | −2.5/2.7 (0.18/0.17) | 13 |
| wt-Cx45/Cx45-tag | −71.9/17.4 (1.9/2.5) | n.d./0.18 (–/0.02) | −2.04/1.61 (0.26/0.20) | 5 |
Means ±1 SEM (in parentheses)
aData taken from Desplantez et al. (2004)
bData taken from Desplantez et al. (2007). For experiments on mixed channels, see electronic supplement
V j,0, V j at which g j,ss is half-maximally inactivated; g j,min, minimal conductance at large V j; z, equivalent number of unitary positive charges q moving through the electric field applied; n, number of cell pairs; n.d., not determined
P values (V j,0, g j,min, z): <0.05, <0.05, <0.0001 (homotypic Cx43); <0.0001, >0.05, <0.05 (homotypic Cx40); <0.0001, >0.05, <0.05 (homotypic Cx45)