Table 1.
Clinical characteristics in the study groups
| Healthy volunteers (N = 1,398) | Asymptomatic patients (N = 136) | P-values | |
|---|---|---|---|
| Age | 58.6 ± 8.6 | 59.2 ± 10.0 | .41 |
| Male | 739 (52.9%) | 104 (76.5%) | <.001 |
| CAD risk factors | |||
| High cholesterol | 817 (58.4%) | 100 (73.5%) | .001 |
| Hypertension | 583 (41.7%) | 74 (54.4%) | .004 |
| Smoking | 91 (6.5%) | 11 (8.1%) | .48 |
| Diabetes | 92 (6.6%) | 22 (16.2%) | <.001 |
| Family history | 382 (27.3%) | 35 (25.7%) | .69 |
| # of CAD risk factors | 1.4 ± 0.9 | 1.7 ± 1.0 | <.0001 |
| BMI | 27.7 ± 5.3 | 28.2 ± 5.3 | .09 |
| Pre-test likelihood of CAD | 6.7 ± 4.0 | 7.9 ± 4.7 | .001 |
| Medication use | |||
| Blood pressure medications | 450 (32.2%) | 59 (43.4%) | .008 |
| Lipid lowering medications | 364 (26.0%) | 56 (41.2%) | <.001 |
| Laboratory values | |||
| Glucose | 96.1 ± 19.0 | 101.2 ± 29.4 | .005 |
| Cholesterol | 215.4 ± 41.6 | 203.0 ± 47.6 | .0001 |
| LDL | 135.6 ± 38.9 | 124.1 ± 41.7 | .0002 |
| HDL | 53.8 ± 16.6 | 51.5 ± 16.2 | .12 |
| Triglycerides | 133.9 ± 84.4 | 135.7 ± 104.3 | .35 |
| FRS | |||
| Mean score | 11.0 ± 7.0 | 13.0 ± 8.2 | .01 |
| FRS < %10 | 618 (56.0%) | 48 (42.9%) | |
| FRS 10%–20% | 319 (28.9%) | 37 (33.0%) | |
| FRS > 20% | 167 (15.1%) | 27 (24.1%) | .01 |
| Resting hemodynamic | |||
| Heart rate (bpm) | 66.3 ± 10.3 | 67.8 ± 12.1 | 0.22 |
| Systolic BP (mmHg) | 133.1 ± 17.5 | 135.3 ± 16.0 | 0.06 |
| Diastolic BP (mmHg) | 82.0 ± 10.7 | 80.0 ± 8.0 | 0.005 |
BP, Blood pressure.