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. 2011 Feb 25;39(4):1235–1251. doi: 10.1007/s10439-011-0280-y

Table 1.

Comparison of 24-h protein synthesis inhibition IC50 values of TGF-α-PE40 and EGF-PE(∆Ia) in a variety of cancer cells with different expression levels of EGFR

Cancer cell line EGFR (# cell−1)65,105 IC50 (ng mL−1)
TGF-α-PE40105 EGF-PE(∆Ia)65
A431 (epidermoid) 3 × 106 0.1 3
KB (nasopharyngeal) 2 × 105 0.2 9
HUT 102 (leukemia) <103 >1000 >200

Data taken from published work by Pastan and coworkers105 and Hwang and coworkers65