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The structural and hydration number (q) changes in the first coordination sphere of Gd(III) of spirooxazine-Gd-DO3A triggered by NADH and hydrogen peroxide. T 1-weighted MRI images of (a) spirooxazine-Gd-DO3A and (b) the mixture of spirooxazine-Gd-DO3A and NADH (Gd:NADH = 1:1), in P388D1 murine macrophages. Images modified from Scheme 2 and Fig. 5 in Tu et al. 80
