Table 2.
Clinical characteristics and plasma S100A12 level of the study groups
| CVD (n = 197) | Non-CVD (n = 353) | P | |
|---|---|---|---|
| Age (years) | 66.1 ± 9.7 | 61.9 ± 13.0 | <0.001a |
| Men/women (n) | 135/62 | 220/133 | 0.145 |
| Current smoker/nonsmoker (n) | 28/169 | 37/316 | 0.194 |
| Duration of HD (years) | 9.2 ± 7.6 | 9.9 ± 8.7 | 0.321 |
| Systolic BP (mmHg) | 145.0 ± 22.9 | 141.7 ± 22.1 | 0.101 |
| Hemoglobin (g/dl) | 10.4 ± 1.2 | 10.3 ± 1.0 | 0.167 |
| White blood cells (/mm3) | 6081 ± 1807 | 5532 ± 1793 | 0.001a |
| Platelet (104/μl) | 17.6 ± 6.38 | 16.3 ± 5.60 | 0.014a |
| hs-CRP (mg/L) | 6.59 ± 10.49 | 2.70 ± 7.65 | <0.001a |
| Creatinine (mg/dl) | 10.0 ± 2.43 | 10.8 ± 2.69 | 0.001a |
| Albumin (g/dl) | 3.7 ± 0.37 | 3.7 ± 0.39 | 0.266 |
| Sodium (mEq/L) | 138.8 ± 3.02 | 139.9 ± 2.83 | <0.001a |
| Potassium (mEq/L) | 4.5 ± 0.72 | 4.6 ± 0.68 | 0.781 |
| Calcium (mg/dl) × phosphate (mg/dl) | 41.7 ± 10.40 | 41.5 ± 10.56 | 0.825 |
| Total cholesterol (mg/dl) | 163.3 ± 43.11 | 161.8 ± 47.32 | 0.715 |
| DN/non-DN (n) | 107/90 | 95/258 | <0.001a |
| Plasma S100A12 (ng/ml) | 33.8 ± 28.1 | 20.2 ± 16.6 | <0.001a |
The data are the means ± SD.
a
Significant independent determinants.