Table 4.
Comparison of baseline characteristics between patients who did and did not reach the combined endpoints of commencement of dialysis or death
| Characteristics | Patients with Endpoint (n = 25) | Patients without Endpoint (n = 120) | P |
|---|---|---|---|
| Age (years) | 72.2 ± 10.7 | 67.8 ± 12.3 | 0.103 |
| Male gender (%) | 68.0 | 68.3 | 0.974 |
| Smoking history (%) | 64.0 | 54.6 | 0.390 |
| Diabetes mellitus (%) | 68.0 | 45.8 | 0.044 |
| Hypertension (%) | 92.0 | 82.5 | 0.368 |
| Coronary artery disease (%) | 28.0 | 16.7 | 0.185 |
| Cerebrovascular disease (%) | 36.0 | 15.8 | 0.020 |
| Systolic BP (mmHg) | 151.9 ± 18.5 | 140.5 ± 21.3 | 0.016 |
| Diastolic BP (mmHg) | 81.4 ± 11.5 | 78.4 ± 11.5 | 0.246 |
| Pulse pressure (mmHg) | 70.5 ± 12.3 | 62.8 ± 17.5 | 0.041 |
| Heart rate (beats/min) | 77.6 ± 9.6 | 73.3 ± 14.3 | 0.161 |
| Body mass index (kg/m2) | 25.8 ± 5.0 | 26.0 ± 4.8 | 0.883 |
| Laboratory parameters | |||
| Albumin (g/dl) | 3.9 ± 0.3 | 4.0 ± 0.3 | 0.050 |
| fasting glucose (mg/dl) | 140.2 ± 61.9 | 117.5 ± 40.9 | 0.089 |
| triglyceride (mg/dl) | 205.6 ± 120.2 | 158.5 ± 92.7 | 0.080 |
| total cholesterol (mg/dl) | 193.9 ± 43.8 | 197.5 ± 44.6 | 0.719 |
| HDL-cholesterol (mg/dl) | 41.8 ± 13.2 | 46.5 ± 13.4 | 0.118 |
| LDL-cholesterol (mg/dl) | 105.8 ± 30.0 | 113.4 ± 34.0 | 0.309 |
| hematocrit (%) | 31.0 ± 4.6 | 37.7 ± 6.4 | <0.001 |
| baseline eGFR (ml/min per 1.73 m2) | 14.4 ± 10.4 | 33.2 ± 13.3 | <0.001 |
| calcium (mg/dl) | 9.3 ± 0.7 | 9.7 ± 0.7 | 0.023 |
| phosphate (mg/dl) | 4.5 ± 1.2 | 3.7 ± 0.7 | 0.002 |
| uric acid (mg/dl) | 8.5 ± 2.3 | 8.2 ± 2.3 | 0.666 |
| PTH (pg/ml) | 102.2 ± 107.1 | 57.8 ± 99.1 | 0.050 |
| Albuminuria (%) | 92.0 | 69.2 | 0.024 |
| baPWVa (cm/s) | 2405.3 ± 711.6 | 1981.7 ± 944.6 | 0.036 |
| Medications | |||
| aspirin use (%) | 37.5 | 26.9 | 0.294 |
| ACEI and/or ARB use (%) | 64.0 | 81.5 | 0.053 |
| β-blocker use (%) | 24.0 | 33.3 | 0.634 |
| calcium channel blocker use (%) | 55.8 | 64.0 | 0.453 |
| diuretic use (%) | 45.0 | 16.0 | 0.007 |
| statin use (%) | 25.0 | 27.7 | 0.784 |
| ESA use (%) | 28.0 | 3.3 | <0.001 |
a
Data were adjusted for mean arterial pressure.