Table 2.
Demographics
| Category | No AKI (n = 357) | AKI (n = 357) | pRIFLE R (n = 291) | pRIFLE I (n = 65) | pRIFLE F (n = 1) |
|---|---|---|---|---|---|
| Age (years) | 7.7 ± 5.4 | 6.7 ± 5.6a | 6.8 ± 5.6a | 6.0 ± 5.5 | 6 |
| Age category (patients) | |||||
| Neonates (1 to 30 days) | 1 | 1 | 1 | 0 | 0 |
| Infants (>30 days to 2 years) | 40 | 40 | 30 | 10 | 0 |
| Children (> 2 to 12 years) | 233 | 233 | 189 | 43 | 1 |
| Adolescents (>12 years) | 83 | 83 | 71 | 12 | 0 |
| Baseline eCCl (ml/min per 1.73 m2) | 139.5 ± 43 | 161.1 ± 78.5a | 152.9 ± 42.9a | 199.7 ± 144.6a | 29.9 |
| Minimum eCCl (ml/min per 1.73 m2) | 135 ± 41.8 | 125.4 ± 46.5a | 125.5 ± 37.7a | 126.7 ± 73.6 | 23.9 |
| Maximum eCCl (ml/min per 1.73 m2) | 164 ± 45.3 | 209.7 ± 94.5a | 190.2 ± 54.4a | 299.9 ± 160.5a | 29.9 |
| Length of hospital stay (days) | 7.1 ± 4.2 | 12.3 ± 9.4a | 11.5 ± 8.3a | 16.1 ± 12.5a | 4 |
| Cost of stay (U.S. dollars) | 48,300 ± 38,800 | 82,600 ± 77,000a | 77,400 ± 69,000a | 107,000 ± 102,000a | 23,000 |
| SCr values per admit day | 0.64 ± 0.28 | 0.73 ± 0.28a | 0.73 ± 0.28a | 0.76 ± 0.25a | 0.89 |
| Patients who received at least one medication (%) | 299 (83.8%) | 316 (88.5%) | 254 (87.3%) | 61 (93.8%) | 1 (100%) |
| Medication exposure (median and range) | 2 (0 to 7) | 2 (0 to 8)a | 2 (0 to 7) | 3 (0 to 8)a | 1 |
| Medication exposure intensity (median and range) | 2 (0 to 6) | 2 (0 to 7)a | 2 (0 to 6) | 3 (0 to 7)a | 1 |
| Days of medication therapy (median and range) | 6 (0 to 75) | 11 (0 to 271)a | 10 (0 to 127)a | 19 (0 to 271)a | 2 |
| Medication doses (median and range) | 12 (0 to 191) | 25 (0 to 562)a | 23 (0 to 302)a | 38 (0 to 562)a | 8 |
| Doses per therapy day | 2.1 ± 1.3 | 2.1 ± 1.2 | 2.4 ± 1.2 | 2.2 ± 1.1 | 4 |
| Medication doses per admission day | 3.1 ± 2.9 | 3.2 ± 2.7 | 3.1 ± 2.7 | 3.5 ± 2.6 | 2 |
a
P < 0.05 compared with patients with no AKI.