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Activity profile of FPA and SPA for PPARγ
IC50 values were determined using data from two independent experiments in triplicate. ND, not determined.
| Compound | FPA: IC50vs. DRIP-2 | SPA: IC50vs. [3H]rosiglitazone |
|---|---|---|
| GW9662 | ND | 0.13 ± 0.01 |
| Rosiglitazone | 0.8 ± 0.2 | 0.48 ± 0.04 |
| 17 | 15 ± 1.7 | 1.7 ± 0.3 |
