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. 2011 Feb 8;286(14):12166–12171. doi: 10.1074/jbc.M110.196584

FIGURE 4.

FIGURE 4.

Rational design of RTA variants. A, stereo diagram showing the overall fold of the RTA. The epitope of mAb 6C2 is colored in blue. B and C, the average fluctuation per residue calculated over the last 40 ns of the trajectory. Root mean square fluctuation values were calculated relative to the starting structure at 300 K (B) and 500 K (C).