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. 2011 Feb 16;286(14):12213–12220. doi: 10.1074/jbc.M110.214619

FIGURE 1.

FIGURE 1.

OxLDL induces BMP-2 expression in human CAECs with a minor effect on the inflammatory response. A, representative immunoblot of four separate experiments and densitometric data show that stimulation of cells with oxLDL for 24 h increased BMP-2 protein levels in human CAECs in a concentration-dependent fashion. Densitometric data are expressed as mean ± S.E. (error bars). n = 4; *, p < 0.05 versus control (no oxLDL). B, representative immunoblot of two separate experiments shows that BMP-2 protein increased at 4 h of oxLDL stimulation (80 μg/ml) and accumulated with prolonged stimulation. C, IL-8 level increased moderately after stimulation with oxLDL (80 μg/ml) for 24 h whereas PGN (10 μg/ml) and LPS (200 ng/ml) induced marked increases in multiple cytokines. Data are expressed as mean ± S.E. n = 4; *, p < 0.05 versus control. D, representative immunoblot of two separate experiments shows that oxLDL (160 μg/ml, 24 h) failed to induce ICAM-1 expression although LPS significantly increased the cellular ICAM-1 level.