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. 2011 Feb 10;286(14):12300–12307. doi: 10.1074/jbc.M110.182741

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — Current knowledge of the proteolytic cascades involving clip-SPs, as described in the literature. The figure depicts the proteolytic cascades of the development and immunity. Left, development in D. melanogaster (D.m. dev.) (3). Center, immunity in D. melanogaster (D.m. immun.) (8, 9). Right, immunity in T. molitor (T.m.) (12) and in M. sexta (M.s.) (15). Arrows indicate experimentally verified direct links. Dashed arrows indicate steps that have not been experimentally verified or in which components of the pathway have not been identified.