TABLE 1.
Protease identified in the siRNA screen
| Gene symbol | Name | Clan/family | Catalytic activity |
|---|---|---|---|
| BLMH | Bleomycin hydrolase | CA/C1 | Cysteine amino-/carboxy-/endopeptidase |
| CTSZ | Cathepsin Z (P, X) (Alternative names Cathepsin P, X) | CA/C1 | Cysteine carboxypeptidase |
| CTSB | Cathepsin B | CA/C1 | Cysteine endopeptidase |
| CTSH | Cathepsin H | CA/C1 | Cysteine endopeptidase |
| CALP10 | Calpain 10 | CA/C2 | Cysteine endopeptidase |
| F2 | Thrombin | PA/S1 | Serine endopeptidase |
| ELA2A | Elastase 2A | PA/S1 | Serine endopeptidase |
| PROZ | Protein Z | PA/S1 | Serine endopeptidase |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 | MA/M11 | Metalloendopeptidase, zinc binding |
| UQCRC2 | Ubiquinol-cytochrome c reductase core protein II | ME/M16 | Metalloendopeptidase, zinc binding |
| RBP3 | Retinol binding protein 2 | Unknown | Unknown |