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Auditory brainstem response (ABR) results after nhMSC transplantation. Click-evoked ABR waves are recorded up to -10 ± 10 dB in normal guinea pigs. Seven days after application of 1 mM ouabain to the round window, an increase of ABR threshold is noted. After receiving a nhMSC transplantation, the auditory neuropathy guinea pigs show a significant improvement in hearing threshold compared to the control group (*P < 0.05).
