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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Immunol. 2010 Mar 15;184(6):2743–2749. doi: 10.4049/jimmunol.0902937

Table I.

Selected antibodies to mouse and human TIM-1 that have been functionally characterized in the literature. Unless otherwise stated, the antibodies recognize murine Tim-1.

Tim-1 Antibodies Epitope Functional Effects Refs.
3B3 IgV Activation; co-stimulation (17)
1H8.2 Mucin/stalk
(BALB/c only)
Increased Th2 (24)
5D1.1 Mucin/stalk
(BALB/c only)
Increased Th2 (24)
3A2.5 Stalk Decreased Th2 (24)
4A2.2 IgV Decreased Th2 (24)
1H9.9 IgV No apparent effects (24)
RMT1-10* IgV Inhibition of T cell responses (25, 50, 51)
3D1 (human) IgV Blocks HAV and PS binding (43, 52)
*

This Tim-1 antibody should not be confused with a commercially available antibody with the same name