Table 1.
Characteristics of studies included in systematic review of maternal BMI and risk of testicular cancer in sons
| Study-year- location |
Study design |
Cases & source |
Controls & source |
Matching cases/controls (Frequency or Individually) |
Maternal BMI assessment |
Newcastle-Ottawa Quality scale score (NOS) |
Moderate BMI group (kg/m2) |
|---|---|---|---|---|---|---|---|
| Pettersson et al (2008) Sweden | Population-based case-control | 293 Retrieved from Swedish Cancer Register | 861 First three men born at the same hospital after a case | No | Pre-pregnancy BMI Collected during antenatal period in Swedish Medical Birth Register | 8/9 | 20–24 |
| Sonke et al (2007) United States | Hospital-based case-control | 144 Retrieved from University Cancer Centre and Tumour Registry | 86 Cases nominated 4+ cancer- free friends that were of same race | No | Pre-pregnancy BMI Self-reported/ Interviewed on phone | 7/9 | 18.5–24.9 |
| Coupland et al (2004) United Kingdom | Population-based case-control | 794 Retrieved from major cancer treatment centres and regional cancer registries | 794 Selected from GP list where case registered | Individually-matched by age | Pregnancy BMI Self-reported/ collected from postal questionnaire | 7/9 | 20–25 |
| Weir et al (2000) Canada | Population-based case-control | 502 Retrieved from Ontario Cancer Registry | 975 Selected from Ontario census data | No | Pre-pregnancy BMI Self-reported/ interviewed on phone | 7/9 | 18–25 |
| Moller et al (1997) Denmark | Population-based case-control | 296 Retrieved from Danish Cancer Registry | 287 Selected from Danish Central Person Register | Frequency-matched by year of birth | Pre-pregnancy BMI Self-reported/ collected from postal questionnaire | 8/9 | 55–59 kg*** |
| Mori et al (1990) Japan | Hospital-based case-control | 37 Retrieved from urological ward records of nine hospitals | 37 Selected from address registers at five public health centres | Individually-matched by year of birth | Pre-pregnancy BMI Self-reported/ collected from postal questionnaire | 5/9 | <25 |
| Depue et al (1983) United States | Population-based case-control | 108 Retrieved from population-based cancer registry | 108 Selected from same neighbourhoods as cases | Individually-matched by year of birth and race | Pre-pregnancy BMI Self-reported/ interviewed on phone | 4/9 | ≥19 |