Table 3.
Odds Ratios From Generalized Estimating Equation Regression Models Assessing Risk Factors for Diarrhea Morbidity Among HIV-exposed Uninfected Infants During the Period 7–24 Months
| Category | Any Diarrhea |
Diarrhea-Related Clinic Visit |
Prolonged Diarrheaa |
|||
| UnadjustedOR (95% CI) | AdjustedOR (95% CI) | UnadjustedOR (95% CI) | AdjustedOR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Feeding practice: | ||||||
| Stopped breastfeeding vs still breastfeeding | 0.9 (0.7–1.0) | - | 1 (0.8–1.3) | - | 1.2 (0.9–1.6) | 1.7 (1.3–2.3)* |
| Maternal characteristics: | ||||||
| Plasma viral load ≥100,000 vs <100,000 copies/ml | 1.1 (0.9–1.4) | - | 1.2 (0.9–1.6) | - | 1.1 (0.8–1.5) | - |
| BMI <18.5 vs ≥18.5 kg/m2 | 1.2 (1–1.6) | - | 1.4 (1–1.8)* | - | 1.8 (1.2–2.5)* | 1.7 (1.2, 2.4)* |
| Sociodemographic factors: | ||||||
| ≥ Second child vs first child | 1.3 (1–1.7)* | - | 1.6 (1.1–2.4)* | 1.6 (1–2.4)* | 0.6 (0.3–1.0)* | 1.8 (1.1–3.1)* |
| ≥1 child ≥5 years old in the household vs none | 1.2 (1–1.5)* | 1.3 (1.1–1.6)* | 1.2 (0.9–1.5) | - | 1.1 (0.8–1.5) | - |
| High school or more (≥8 years) vs <8 years | 0.8 (0.7–1.0) | - | 0.8 (0.6–1.0) | - | 0.8 (0.6–1.1) | - |
| Electricity in the home | 0.7 (0.6–0.9)* | 0.7 (0.6–0.9)* | 0.7 (0.6–.9)* | 0.8 (0.6–1.0)* | 0.7 (0.5–1.0)* | - |
| Full-time paid job vs part time job or unemployed | 1 (0.7–1.4) | - | 1.1 (0.7–1.7) | - | 1 (0.6–1.6) | - |
| ≥1 day without food at home 1 month before baseline | 1.2 (1–1.5) | - | 1.5 (1.1–1.9) | 1.4 (1–1.8) | 1.3 (0.9–1.8) | - |
| Rainy season vs dry season | 1.5 (1.3–1.8)* | 1.5 (1.3–1.8)* | 1.7 (1.4–2.0)* | 1.7 (1.4–2.1)* | 1.7 (1.3–2.3)* | 1.7 (1.3–2.2)* |
NOTE. Separate regression analyses are shown for each of the 3 outcomes: any diarrhea, diarrhea-related clinic visit, and prolonged diarrhea. Table displays odds ratios (ORs) and 95% confidence intervals (CIs) from generalized estimating equation (GEE) models. ORs marked with an asterisk are significant at P < .05. The adjusted ORs are adjusted for the other factors shown in the adjusted column of the table as well as for age.
Prolonged diarrhea is defined as a diarrheal episode lasting at least 7 days.