A, KIR3DS1/3DL1 genotypes in human immunodeficiency virus–exposed seronegative individuals (Human Immunodeficiency Virus-exposed seronegative [HESN]; n = 44), HIV-infected patients (Human Immunodeficiency Virus [HIV]; n = 192), and unexposed healthy control participants ( n = 103). *pc = .02 between HESN and HIV-infected individuals; pc = .02 between HESN individuals and healthy controls. B, KIR3DS1/3DL1 genotypes in Bw4 carriers (HESN, n = 29; HIV, n = 118; healthy controls, n = 64). *pc = .01 between HESN and HIV; pc = .04 between HESN individuals and healthy controls. C, KIR3DS1/3DL1 genotypes in Bw4-negative participants (HESN, n = 15; HIV, n = 74; healthy controls, n = 39).