Figure 3.

Average figure of merit corrected for bias after phasing versus cosine of the mean phase error (CPEM) for each data set after 20 cycles of β-­corrected density modification by (a) Parrot and (b) SOLOMON. The phasing bias-corrected figure of merit is defined as m _corr = m − [m _ph − cos(δϕ_ph)], where m is the figure of merit after density modification, m _ph is the figure of merit after experimental phasing and δϕ_ph is the phase error after phasing.