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. 2011 Mar;178(3):1201–1209. doi: 10.1016/j.ajpath.2010.11.073

Figure 1.

Figure 1

Gal-1 displays anti-inflammatory effects in the CG-induced paw edema model. A: sGal-1 (3 μg equivalent to 214 pmol) was either given intravenously (i.v.) 30 minutes before CG, or co-administered with CG subplantar (s.pl) into the right paw. An equal volume of saline was given s.pl into the left paw and the edema profile was monitored for 96 hours. Paw volume was assessed by plethysmography and edema calculated as the difference between CG and PBS injected paws. Data are expressed as mean ± SEM of six mice per treatment. *P < 0.05, **P < 0.01, as compared to WT (CG alone). B: Myeloperoxidase activity of paw tissue homogenates obtained 4 hours after injection with CG alone, CG+Gal-1, or PBS alone. Values are expressed as optical density units per mg of protein. Data are expressed as mean ± SEM of three mice per treatment. *P < 0.05, **P < 0.01, as compared to WT (CG alone).