Skip to main content
. 2011 Mar;178(3):1201–1209. doi: 10.1016/j.ajpath.2010.11.073

Figure 5.

Figure 5

Cleaved caspase-3 expression as a marker of apoptosis. Immunohistochemistry was performed for cleaved caspase-3 expression on CG treated paws from WT (A, B), Gal-1−/− (C, D), and WT (E, F) (treated with sGal-9 30 μg, 24 hours after CG induction, see Figure 4B) mice from the 96-hour time point, respectively. Images shown are representative of six mice per group with similar results. Scale bar = 200 μm (A, C, E) 50 μm (B, D, F). G: Quantification of caspase-3 positive cells was carried out in a double-blinded manner, with six fields per section evaluated. *P < 0.05, ***P < 0.001 as compared to WT.