Table 2.
Cytokine | WT (relative expression) | Gal-1−/− (relative expression) |
---|---|---|
IL-1β | 320 ± 61.79‡∥ | 23.47 ± 6.09 |
TNF-α | 37.46 ± 7.03‡ | 23.58 ± 6.28⁎ |
IL-6 | 41.5 ± 15.27 | 13.17 ± 3.40 |
iNOS | 103.64 ± 27†¶ | 5.47 ± 1.57 |
IL-10 | 34.04 ± 7.05† | 44.98 ± 7.67‡ |
TGF-β | 12.21 ± 6.08⁎ | 25.47 ± 2.60‡⁎⁎ |
Real-time PCR analysis for TNF-α, IL-1β, IL-6, iNOS, IL-10, and TGF-β mRNA levels was performed on CG-treated paws of WT and Gal-1−/− mice collected at the 96-hour time-point. Data are expressed as mean ± SEM (8 per group).
§P < 0.05,
P < 0.05,
P < 0.01,
P < 0.001 as compared to control (WT Naïve),
P < 0.01,
P < 0.001 as compared to Gal-1−/−,
P < 0.01 as compared to WT.