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. 2011 Jan;178(1):245–252. doi: 10.1016/j.ajpath.2010.11.040

Figure 6.

Figure 6

Simvastatin improves glycemic control. RhoB−/−, RhoB+/−, and RhoB+/+ animals were injected with simvastatin 2 days before the first STZ injection and for 14 consecutive days. Simvastatin succeeded in bringing the level of hyperglycemia down in all groups (dashed lines, animals treated with simvastatin and STZ; solid lines, animals treated with STZ and vehicle). Values are the mean ± SE. The SE (n = 16 to 30) is shown as the error bar. RhoB+/+, n = 10; RhoB+/−, n = 16; RhoB−/−, n = 11; simvastatin-RhoB+/+, n = 7; simvastatin-RhoB+/−, n = 13; simvastatin-RhoB−/−, n = 21. *P < 0.05 versus the same genotype injected with simvastatin.