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Semi-thin cross-section of the sciatic nerve in wild-type (A), tau−/− (B), Tg30 (C), and Tg30xtau−/− mice (D). The total number of axons (E), mean cross-sectional area (F), and density of axons (G) were similar in wild-type and tau−/− mice, but reduced in Tg30 and Tg30xtau−/− mice. *P <0.05 and *** P <0.001 by one-way ANOVA with Bonferroni post hoc tests (n = 3 for wild-type; n = 4 for tau−/−; n = 6 for Tg30 and Tg30xtau−/−). Scale bar, 50 μm (A–D).
