Table 2.
Correlation Between Methylation Status of CA9 and Clinicopathologic Features
| Variable | Methylation status of CA9 |
P value | |
|---|---|---|---|
| Methylation (n = 36) | Unmethylation (n = 41) | ||
| Age, mean (SD), years | 65.6 (11.4) | 67.6 (14.4) | 0.510 |
| Sex, M/F | 25/11 | 26/15 | 0.635 |
| Histologic type, intestinal/diffuse | 8/28 | 22/19 | 0.006 |
| Intestinal metaplasia, no/yes | 20/16 | 10/31 | 0.009 |
| Depth of cancer invasion, T1,2/T3,4 | 7/29 | 15/26 | 0.131 |
| Lymph node metastasis, no/yes | 7/29 | 1/40 | 0.022 |
| Lymphatic invasion, no/yes | 2/34 | 2/39 | 1.000 |
| Vascular invasion, no/yes | 14/22 | 16/25 | 1.000 |
| Stage, II/III–IV | 5/31 | 2/39 | 0.242 |
| Adjuvant chemotherapy, no/yes | 11/25 | 12/29 | 1.000 |
| CA IX, high/low | 12/24 | 27/14 | 0.006 |
Unless otherwise indicated, data are given as number of patients.
M, male; F, female.