Table 3.
Biochemical Recurrence-Free Survival in the Gleason 7 Subset
| Cox PH model | HR (95% CI) | P-value |
|---|---|---|
| RSG (continuous) | ||
| Univariate | 1.05 (1.02–1.09) | 0.0052 |
| Multivariate⁎ | 1.84 (1.13–3.00) | 0.0140 |
| RSG (grouped) | ||
| Univariate | ||
| >40% vs. 0%–40% | 1.83 (1.20–2.78) | 0.0047 |
| Multivariate⁎ | ||
| >40% vs. 0%–40% | 1.99 (1.23–3.22) | 0.0051 |
CI, confidence interval; Cox PH, Cox proportional hazards regression model; HR, hazard ratio; RSG, reactive stromal grade.
⁎
The multivariate model included log of the variables PSA (prostate-specific antigen), LN (lymph node) metastasis, ECE (extracapsular extension), SVI (seminal vesicle involvement), positive surgical margins, age at surgery, UICC/AJCC tumor-node-metastasis stage, and Gleason Score.