Table 1.
MTAP Immunoreactivity in HCC Tissue of 140 Patients in Relation to Clinicopathological Characteristics
| MTAP IR |
||||||
|---|---|---|---|---|---|---|
| Variable | Categorization | n | % | Negative | Positive | P value⁎ |
| Age at diagnosis | ||||||
| <60 years | 52 | 37.1 | 17 | 35 | 0.157 | |
| ≥60 years | 88 | 62.9 | 40 | 48 | ||
| Sex | ||||||
| Female | 21 | 15.0 | 10 | 11 | 0.483 | |
| Male | 119 | 85.0 | 47 | 72 | ||
| Tumor stage | ||||||
| pT1 | 47 | 33.6 | 13 | 34 | 0.032 | |
| pT2 | 42 | 30.0 | 15 | 27 | ||
| pT3 | 46 | 32.9 | 25 | 21 | ||
| pT4 | 3 | 2.1 | 2 | 1 | ||
| nd | 2 | 1.4 | ||||
| Histological grade | ||||||
| G1 | 53 | 37.9 | 15 | 38 | 0.019 | |
| G2 | 70 | 50.0 | 31 | 39 | ||
| G3 | 17 | 12.1 | 11 | 6 | ||
| Tumor size | ||||||
| ≤5 cm | 70 | 50.0 | 23 | 47 | 0.339 | |
| >5 cm | 40 | 34.3 | 20 | 28 | ||
| nd | 30 | 15.7 | ||||
IR, immunoreactivity; nd, no data available.
⁎
Fisher's exact test (2-sided); boldface indicates P values ≤0.05.