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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Mol Biol. 2010 Jul 23;402(2):399–411. doi: 10.1016/j.jmb.2010.07.036

Fig. 4.

Fig. 4

Stereoviews of enzyme bound to UDP-galactose. (a) Wild-type GTB9 and (b) Cys-to-Ser mutant enzymes. Cyan spheres represent Mn2+. (c) Compared to wild type (yellow), this novel UDP-Gal conformation (green) displaces the closed conformation of the internal loop by steric hindrance of Trp181 and inhibition of C-termini closure by rotation of β-phosphate out of Arg352 access.