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HCV RNA Detection in Cells from Treatment-Naïve, Chronic HCV Patients
| Positive-strand frequency | Negative-strand frequency | |
|---|---|---|
| B-cells (CD19) | 15/50 (30%) | 2/50 (4%) |
| Monocytes (CD14) | 3/42 (7%) | 0/42 (0%) |
| CD19/CD14-depleted PBMC | 2/42 (5%) | 1/42 (2%) |
| Healthy subject B-cells | 0/23 (0%) | 0/23 (0%) |
| Healthy subject B-cells pre-exposed in vitro to HCV-positive serum | 0/4 (0%) | 0/4 (0%) |
PBMC, peripheral blood mononuclear cell; HCV, hepatitis C virus.
