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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Dent Mater. 2011 Feb 26;27(5):465–477. doi: 10.1016/j.dental.2011.01.008

Table.

Changes in lesion depth, lesion surface relative mineral content and ΔZ in artificial lesions (with or without dentin adhesive) remineralized biomimetically using sodium trimetaphosphate as a templating analog of matrix phosphoproteins

Parameter Time
period
Without adhesive *
(N = 8)
With adhesive *
(N = 8)
Lesion depth (µm) Baseline 291.4 ± 7.3 291.9 ± 7.0
1 month 211.8 ± 7.5 246.4 ± 26.4
2 months 158.1 ± 19.3 205.8 ± 28.7
3 months 119.7 ± 15.1 179.9 ± 24.6
4 months 77.2 ± 9.4 138.6 ± 20.9

Changes in lesion depth after 4 months (%) 73.5 ± 3.0 A 52.6 ± 6.7 B

Relative mineral content along lesion surface (vol%) Baseline 11.1 ± 1.6 10.8 ± 1.1
1 month 18.4 ± 1.8 12.0 ± 3.7
2 months 26.4 ± 4.5 14.1 ± 2.8
3 months 37.8 ± 4.3 18.0 ± 5.7
4 months 41.4 ± 6.1 21.0 ± 8.7

Changes in relative mineral content along lesion surface after 4 months (%) 30.2 ± 2.9a 11.0 ± 3.5 b

ΔZ (µm.vol%) Baseline 5312.2 ± 409.6 5685.3 ± 248.8
1 month 3704.2 ± 369.2 4998.8 ± 384.8
2 months 2123.1 ± 430.0 4218.1 ± 537.2
3 months 1127.8 ± 357.1 3390.0 ± 503.6
4 months 489.4 ± 153.3 2486.0 ± 613.6

Changes in ΔZ after 4 months (µm.vol%) 4822.9 ± 324.0 3198.4 ± 440.8

Remineralization efficacy after 4 months (%) ** 90.9 ± 2.5 1 56.6 ± 9.5 2
*

Values are means ± standard deviations. For each parameter summary, groups with different upper case letters, lower case letters or numerals are significantly different (p < 0.05)

**

Remineralization efficacy = (ΔZ baseline – ΔZ 4 months)/ΔZ baseline*100%], where ΔZ represents the integrated mineral loss from the artificial carious lesion