. Author manuscript; available in PMC: 2012 May 1.

Published in final edited form as: Dent Mater. 2011 Feb 26;27(5):465–477. doi: 10.1016/j.dental.2011.01.008

Table.

Changes in lesion depth, lesion surface relative mineral content and ΔZ in artificial lesions (with or without dentin adhesive) remineralized biomimetically using sodium trimetaphosphate as a templating analog of matrix phosphoproteins

Parameter	Time period	Without adhesive ^* (N = 8)		With adhesive ^* (N = 8)
Lesion depth (µm)	Baseline	291.4 ± 7.3		291.9 ± 7.0
	1 month	211.8 ± 7.5		246.4 ± 26.4
	2 months	158.1 ± 19.3		205.8 ± 28.7
	3 months	119.7 ± 15.1		179.9 ± 24.6
	4 months	77.2 ± 9.4		138.6 ± 20.9

	Changes in lesion depth after 4 months (%)		73.5 ± 3.0 ^A		52.6 ± 6.7 ^B

Relative mineral content along lesion surface (vol%)	Baseline	11.1 ± 1.6		10.8 ± 1.1
	1 month	18.4 ± 1.8		12.0 ± 3.7
	2 months	26.4 ± 4.5		14.1 ± 2.8
	3 months	37.8 ± 4.3		18.0 ± 5.7
	4 months	41.4 ± 6.1		21.0 ± 8.7

	Changes in relative mineral content along lesion surface after 4 months (%)		30.2 ± 2.9^a		11.0 ± 3.5 ^b

ΔZ (µm.vol%)	Baseline	5312.2 ± 409.6		5685.3 ± 248.8
	1 month	3704.2 ± 369.2		4998.8 ± 384.8
	2 months	2123.1 ± 430.0		4218.1 ± 537.2
	3 months	1127.8 ± 357.1		3390.0 ± 503.6
	4 months	489.4 ± 153.3		2486.0 ± 613.6

	Changes in ΔZ after 4 months (µm.vol%)		4822.9 ± 324.0		3198.4 ± 440.8

	Remineralization efficacy after 4 months (%) ^**		90.9 ± 2.5 ¹		56.6 ± 9.5 ²

Values are means ± standard deviations. For each parameter summary, groups with different upper case letters, lower case letters or numerals are significantly different (p < 0.05)

^**

Remineralization efficacy = (ΔZ _baseline – ΔZ _{4 months})/ΔZ _baseline*100%], where ΔZ represents the integrated mineral loss from the artificial carious lesion