Fig. 5.
Immunohistochemistry of Sema4C and phosphorylated p38 MAPK on serial sections of rats or patients with renal fibrosis. Sema4C and p38 MAPK were co-expressed in tubules from rats or patients with tubulointerstitial fibrosis. These were representative photomicrographs from kidneys of sham rats immunostained with Sema4C (A) or p-p38 MAPK (B), 5/6-nephrectomized rats immunostained with Sema4C (C) or p-p38 MAPK (D), patients with sclerosing glomerulonephritis immunostained with Sema4C (E) or p-p38 MAPK (F) and patients with obstructive nephropathy immunostained with Sema4C (G) or p-p38 MAPK (H). Magnification, × 200.