Table 5.

Estimates of Effects of SCEI Intervention on Quality of Life and Problem-Solving Skills Based on Random Effects Models Assuming Constant Change per Month that May Differ Between Treatment Groups (primary hypothesis)

Outcome measure	Model-based estimate	Standard error	p value: for parameter = 0
Quality of life (0–100 scale)
Patients
Baseline level	63.4	0.70	<0.001
Change per month in QOL, usual care group	−0.53	0.23	0.02
Effect of SCEI on change/moa	−0.10	0.27	0.70
Caregivers
Baseline level	61.7	0.64	<0.001
Change per month in QOL, usual care group	−0.87	0.19	<0.001
Effect of SCEI on change/moa	0.50	0.22	0.02
Problem-solving skills
Patients
Baseline level	104.6	0.69	<0.001
Change per month in problem solving, usual care	−0.53	0.21	0.01
Effect of SCEI on change/moa	−0.04	0.24	0.86
Caregivers
Baseline level	106.5	0.65	<0.001
Change per month in problem solving, usual care	−0.23	0.21	0.28
Effect of SCEI on change/moa	−0.30	0.24	0.21

Models allow for different baseline levels and length of follow-up.

^aEstimates of difference between rate of change per month under usual care and rate of change under SCEI intervention. Positive values indicate higher (more favorable) levels for the SCEI intervention, with slower decline in the outcome, while negative values indicate faster decline in the outcome compared to usual care.

SCEI, Simultaneous Care Educational Intervention; QOL, quality of life.