Table 2.
Urodynamic Parameters by Cystometry and Bladder Weight
Parameter | Sham (n=4) | Control (n=10) | hGRP (n=9) | hGDA (n=6) |
---|---|---|---|---|
Residual urine (mL) | 0±0 | 0.12±0.08 | 0.42±0.13 | 0.13±0.08 |
Micturition pressure (mm Hg) | 15.58±2.58 | 42.32±4.07* | 36.21±1.72* | 37.21±2.04* |
DHR (no. of episodes/micturition) | 0.25±0.15 | 16.36±5.57* | 6.25±0.79# | 19.25±1.70* |
Bladder capacity (mL) | 0.33±0.03 | 0.60±0.20 | 1.04±0.10*# | 0.53±0.05 |
Bladder weight:body weight ratio (g) | 0.61±0.02 | 1.3±0.07* | 1.43±0.09* | 1.38±0.08* |
Significantly different from sham animals, p<0.05.
Significantly different from control animals, p<0.05.
DHR, detrusor hyperreflexia; hGRP, human glial-restricted progenitor; hGDA, astrocytes derived from hGRP.