FIG. 1.

(A–C) Neuropathological scores of the brain regions after bilateral common carotid artery occlusion (BCCAO). The individual scores are plotted as dots and the mean values are presented as columns. Ischemic injuries in the 22-min group (B) were much more severe compared with those in the 15-min group (A). Consistent injury was observed, especially in the striatum. The severity of the injury in the 30-min group (C) was similar to that seen in the 22-min group. (D) Frequency of ischemic injury in the brain regions. Bilateral injury to the striatum was observed in 80%, while injury to the CA1 subregion was seen in 40% (DG, dentate gyrus; Ctx, cortex; Thal, thalamus; Str, striatum).