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Genetic organization of T4SSs discussed in detail in this review. Homology to the virB/D4 system is indicated by the text in grey above the schemes, e.g. B4 above a gene means that this gene is homologous to virB4. Genes in blue corresponds to plausible core components, in green ATPases, in yellow plausible surface components, in orange lytic tranglycosylases and in red effector proteins. For L. pneumophila, upper-case gene names = Dot and lower-case gene names = Icm.
