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Hemodynamic parameters and circulating leukocyte counts in wild-type and MIF−/− mice treated with LPS (100 ng) and DEX*
| Shear rate (s−1) |
Leukocyte count (×10−6/mL) |
|
|---|---|---|
| Wild-type mice | ||
| LPS (n=6) | 462 ± 39 | 4.7 ± 0.6 |
| LPS + DEX (n=5) | 498 ± 51 | 1.7 ± 0.2† |
| MIF−/− mice | ||
| LPS (n=6) | 710 ± 61τ | 9.9 ± 0.6τ |
| DEX (n=6) | 705 ± 92 | 4.9 ± 0.8† |
Data are shown as mean ± sem.
denotes p < 0.05 versus wild-type mice receiving the same treatment.
denotes p < 0.05 versus LPS alone treatment.
