Table 2.
entry | RCHO | Conditions, yield | Product | |
---|---|---|---|---|
Thermal | SnBr4 (10 mol %), rt | |||
1 | PhCHO | 100 °C, 18 h, 77% | 3 h, 37% | 5 |
2 | n-BuCHO | 100 °C, 18 h, 72% | 3 h, 37% | 19 |
3 | i-PrCHO | 130 °C, 3 d, 73% | 18 h, 40% | 20 |
4 | 130 °C, 5 d, 72% | 18 h, 94% | 21 | |
5 | 100 °C, 18 h, 80% | decomposition | 22 |
Products were formed as one isomer as detected by 1H NMR spectroscopy and GCMS. Yields reported are isolated yields.