Table 1.

E2 Targets in Osteoblasts

Target	Regulation	Time	Cell type	Reference
FasL	⇑	3 hours	Mouse calvarial osteoblasts	[Krum et al., 2008a]
Alkaline phosphatase	⇑	3 hours	Mouse calvarial osteoblasts	[Krum et al., 2008b]
Bcl-2	⇑	24 hours	Mouse calvarial osteoblasts	[Pantschenko et al., 2005].
OPG	⇑	24 hours	Primary human osteoblasts	[Bord et al., 2003]
Rbbp1	⇑	4 hours	Mouse calvarial osteoblasts	[Monroe et al., 2006]
BMP-2	⇑	24 hours	Mouse MSCs differentiated to OBs	[Zhou et al., 2003]
IGFBP4	⇑	24 hours	Primary human osteoblasts	[Denger et al., 2008]
ERα	⇑	24 hours	Primary human osteoblasts	[Bord et al., 2003]
TGF-β3	⇑	2 hours	Rat femora	[Yang et al., 1996]