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tracrRNA-mediated crRNA maturation is inherent to the type II (Nmeni/CASS4) CRISPR/Cas systems. Type II (Nmeni/CASS4) loci from S. pyogenes SF370, S. mutans UA159, L. innocua Clip11262, N. meningitidis Z2491 and S. thermophilus LMD-9 (Nmeni/CASS4a); red, tracrRNA; rectangles, repeats; diamonds, spacers.
