Fig. 4.

A, A quantitative RT-PCR array including 84 genes involved in oncogenesis demonstrated that key oncogenes were overexpressed in the larger nodules when compared with smaller AIMAH nodules; B, a small and large nodule from patient 2, stained by hematoxylin and eosin (magnification, ×5): BCL-2 and c-KIT were highly expressed in the large nodule but not as much in the smaller nodule (magnification, ×10); C, strong CTNNB1 staining in a large nodule and weak staining in the small nodule (magnification, ×10).