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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Oncol Rep. 2011 Feb 24;25(5):1329–1335. doi: 10.3892/or.2011.1195

Figure 4.

Figure 4

TGF-β1 promotes the expression of ADAM17 in T98G. (A) T98G glioma cells were plated in 6-well plates, and then treated with TGF-β1 (1ng/ml) for the times showed. The mRNA levels of ADAM17 in T98G glioblastoma cells were up-regulated by TGF-β1. The levels of ADAM17 mRNA were determined by Real-time RT-PCR. *P< 0.01 compared with 0h. (B) T98G glioma cells were incubated with TGF-β1 (1ng/ml) in the presence or absence of SB (10nmol/ml) or TAPI-2 (100nmol/ml), and the total protein was harvested for western blotting analysis with antibodies against ADAM17 and β-actin.