Table 2.
1H NMR Data for Compounds 7 - 12 in CD3OD at 600 MHz
| cmpd. | 7 | 8 | 9 | 10 | 11 | 12 |
|---|---|---|---|---|---|---|
| pos # | δ H (J[Hz]) | δH (J[Hz]) | δH (J[Hz]) | δH (J[Hz]) | δH (J[Hz]) | δ H (J[Hz]) |
| 2 | 2.74, dd (15.2, 4.0) | 2.72, dd (15.4, 4.0) | 3.01, dd (15.6, 9.0) | 3.05, dd (15.8, 9.4) | 3.03, dd (15.8, 9.0) | |
| 2.63, dd (15.2, 9.0) | 2.69, dd (15.4, 8.6) | 2.78, dd (15.6, 6.0) | 2.83, dd (15.8, 5.8) | 2.83, dd (15.8, 5.6) | ||
| 3 | 5.26, dd (9.0, 4.0) | 5.25, dd (8.6, 4.0) | 5.37, dd (9.0, 6.0) | 5.36, dd (9.4, 5.8) | 5.36, dd (9.0, 5.6) | |
| 5 | 5.55, dd (9.0, 7.2) | 5.63, dd (9.5, 7.0) | 5.65, dd (11.4, 4.8) | 5.64, dd (11.4, 4.8) | 5.65, dd (11.4, 4.8) | 5.67, dd (11.6, 4.8) |
| 7 | 4.76, q (6.6) | 4.72, q (6.6) | 4.37, q (7.0) | 4.35, q (7.0) | 4.37, q (6.8) | 4.45, q (7.0) |
| 9 | 2.70, m | 2.69, m | 2.46, m | 2.46, m | 2.47, m | 2.46, m |
| 10 | 2.22, dd (15.4, 11.4) | 2.21, dd (15.4, 11.6) | 2.26, dd (13.4, 5.6) | 2.25, dd (13.4, 5.4) | 2.26, dd (13.4, 5.2) | 2.24, dd (13.5, 6.0) |
| 1.97, d (15.4) | 1.95, br d (15.4) | 1.89, dd (13.4, 9.6) | 1.86, dd (13.4, 9.4) | 1.88, dd (13.4, 9.6) | 1.90, dd (13.5, 8.0) | |
| 12 | 4.90a | 4.88a | 4.91, d (9.6) | 4.89a | 4.91a | 4.93a |
| 13 | 2.34, dddq (9.6, 9.6, 8.4, 5.4) | 2.32, dddq (9.0, 9.0, 8.4, 5.4) | 2.46, m | 2.46, m | 2.47, m | 2.46, m |
| 14 | 1.54, ddd (13.2, 9.8, 5.8) | 1.52, ddd (13.2, 9.6, 6.0) | 1.44, ddd (13.4, 8.4, 6.6) | 1.44, ddd (13.2, 8.4, 6.4) | 1.45, ddd (13.2, 8,4, 6.6) | 1.42, ddd (13.4, 8.2, 6.6) |
| 1.23, ddd (13.2, 8.2, 5.4) | 1.22, ddd (13.2, 8.4, 5.4) | 1.29, dd (13.4, 6.8) | 1.28, ddd (13.2, 6.6, 6.6) | 1.29, ddd (13.2, 6.6, 6.6) | 1.28, ddd (13.4, 6.6, 6.6) | |
| 15 | 4.71, qdd (6.2, 6.0, 6.0) | 4.72, m | 3.69, ddq (6.8, 6.6, 6.2) | 3.68, ddq (6.6, 6.4, 6.2) | 3.64, ddq (6.6, 6.6, 6.2) | 3.68, ddq (6.6, 6.6, 6.0) |
| 17 | 6.91, d (8.5) | 6.95, d (8.5) | 7.18, d (8.5) | 7.16, d (8.5) | 7.16, d (8.5) | |
| 18 | 6.66, d (8.5) | 6.68, d (8.5) | 6.71, d (8.5) | 6.71, d (8.5) | 6.72, d (8.5) | |
| 20 | 3.28a | 3.25, dd (15.0, 7.0) | 3.43, dd (15.2, 4.8) | 3.43, dd (15.2, 4.8) | 3.43, dd (15.0, 4.8) | 3.39, dd (15.2, 4.8) |
| 3.15, dd (15.0, 7.2) | 3.16, dd (15.0, 9.5) | 3.13, dd (15.2, 11.4) | 3.12, dd (15.2, 11.4) | 3.13, dd (15.0, 11.4) | 3.18, dd (11.6, 15.2) | |
| 23 | 7.59, dt (8.0, 1.0) | 7.48, d (8.5) | 7.50, dt (8.0, 1.0) | 7.49, dt (8.0, 0.6) | 7.50, d (8.0) | 7.53, dt (8.0, 0.8) |
| 24 | 7.01, td (8.0, 1.0) | 7.12, dd (8.5, 1.5) | 6.99, td (8.0, 1.0) | 6.99, td (8.0, 1.0) | 7.01, td (8.0, 0.8) | 7.01, td (8.0, 0.8) |
| 25 | 7.09, td (8.0, 1.0) | 7.06, td (8.0, 1.0) | 7.05, td (8.0, 1.0) | 7.07, td (8.0, 0.8) | 7.07, td (8.0, 0.8) | |
| 26 | 7.32, dt (8.0, 1.0) | 7.42, d (1.5) | 7.23, dt (8.0, 1.0) | 7.23, dt (8.0, 0.6) | 7.23, d (8.0) | 7.24, dt (8.0, 0.8) |
| 28 | 7.00, s | |||||
| 29 | 0.92, d (6.6) | 0.79, d (6.6) | 0.65, d (7.0) | 0.66, d (7.0) | 0.66, d (6.8) | 0.58, d (7.0) |
| 30 | 1.11, d (6.8) | 1.09, d (6.8) | 0.98, d (7.0) | 0.97, d (6.8) | 0.98, d (6.8) | 0.97, d (7.0) |
| 31 | 1.61, s | 1.60, s | 1.57, d (1.0) | 1.57, d (1.2) | 1.58, s | 1.57, d (1.2) |
| 32 | 0.87, d (6.6) | 0.86, d (6.6) | 0.91, d (6.6) | 0.90, d (6.6) | 0.91, d (6.6) | 0.89, d (6.6) |
| 33 | 1.06, d (6.2) | 1.08, d (6.6) | 1.11, d (6.2) | 1.11, d (6.2) | 1.12, d (6.2) | 1.11, d (6.0) |
| 34 | 3.09, s | 3.11, s | 3.08, s | 3.06, s | 3.07, s | 3.06, s |
| 35 | 3.65, s | 4.11, q (7.2) | ||||
| 36 | 1.22, t (7.0) | |||||
a
Shift assigned based on gHMQC and gHMBC data.