Table 5.
Selected NCI 60 Cell Line Screening Results for Compounds 1, 4-9, 11 and 13.
| cell line | IGROV-1 | U25-1 | NCI-H522 | DU-145 | A498 | LOX-IMVI | 
|---|---|---|---|---|---|---|
| cell type | Ovarian | CNS | Lung | Prostate | Renal | Melanoma | 
| cmpd. | GI50 (μM) | |||||
| 1 | 0.02 | 0.07 | 0.03 | 0.03 | 0.03 | 0.01 | 
| 4 | 0.008 | 0.01 | 0.03 | 0.02 | 0.002 | 0.003 | 
| 5 | 0.02 | 0.05 | 0.61 | 0.29 | 0.21 | 0.03 | 
| 6 | 0.03 | 0.06 | 0.20 | 0.25 | 0.17 | 0.02 | 
| 7 | 0.01 | 0.03 | 0.16 | 0.10 | 0.08 | 0.02 | 
| 8 | 0.03 | 0.03 | 0.003 | 0.31 | 0.04 | 0.04 | 
| 9 | 1.76 | 0.60 | 0.12 | 18.8 | NTa | 0.28 | 
| 11 | 0.17 | 0.05 | 0.04 | 3.72 | 0.44 | 0.16 | 
| 13 | 0.03 | 0.04 | 0.06 | 0.08 | 0.01 | 0.007 | 
NT=not tested