Figure 3.
Typical PK/PD viral kinetics profiles with weekly subcutaneous injections of 180 μg of peg-IFNα-2a (left) and 1.5μg/kg of peg-IFNα-2b (right); viral load (black) and serum peg-IFN concentration (green). The PK parameters have been obtained using median values given in (23) and the PD parameters are the median values for peg-IFNα-2a and a typical patient for peg-IFNα-2b in (21-22).