Table 1.

Atorvastatin-associated liver disorders: Clinical details of patients in this report.

	Case 1	Case 2
Coexisting diseases	coronary heart disease, hypertension, systemic lupus erythematosus, old pulmonary tuberculosis	coronary heart disease, non-alcoholic fatty liver disease, mixed hyperlipidemia
Combined drugs	prednisone, hydroxychloroquine, bay-aspirin, clopidogrel, low molecular weight heparin, isosorbide dinitrate, metoprolol	bay-aspirin, clopidogrel, low molecular weight heparin, isosorbide dinitrate, metoprolol
HBsAg and HCV-Ab	negative	negative
Symptoms after ATV	obvious fatigue, anorexia	no symptoms
Peak ALT (n < 40 U/l)	120	278
Peak AST (n < 40 U/l)	23	119
Peak GGT (n < 67 U/l)	40	124
Peak ALP (n < 120 U/l)	62	93
Peak LDH (n < 270 U/l)	148	171
Peak direct bilirubin (n < 8.6 μmol/l)	3.7	1.9
Peak total bilirubin (n < 22 μmol/l)	9.2	9.3
RUCAM score	7	7

HBsAg = hepatitis B surface antigen; HCV-Ab = hepatitis C virus antibody; ATV = atorvastatin; ALT = alanine aminotransferase; AST = aspartate aminotransferase; LDH = lactate dehydrogenase; GGT = gamma-glutamyl transpeptidase; ALP = alkaline phosphatase; RUCAM = Roussel-Uclaf causality assessment method; n = normal range.