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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Biochemistry. 2011 Mar 10;50(13):2701–2709. doi: 10.1021/bi200279s

Figure 2.

Figure 2

Potential energy surfaces for the reaction of arsenate with inosine and phosphate with inosine are shown above. The similarity in the surfaces (RMSD = 0.982) supports the ability of arsenate to mimic phosphate in the PNP reaction.