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(A) Intrinsic KIEs and their standard errors for Phe200Gly HsPNP-catalyzed arsenolysis (blue) and phosphorolysis (red) of inosine, and WT-HsPNP catalyzed (black) arsenolysis of inosine (10). Between parentheses is the number of replicates. (B) Predicted KIEs for the best match non-stationary point TS for arsenolysis (blue) and phosphorolysis (red) of inosine. The labels and their respective positions are shown in cyan.
