Table 2.
Frequency of Ala592Thr variant in various populations of breast cancer patients and control population
| No of families/ | Frequency of | |||
| Screened population | no of cases | Ala592Thr variant | Case id | Histopathology |
| Familial breast cancer | ||||
| Non-BRCA1/BRCA2 mutation carrier | 358 | 0.56% | 311-89D | Ductal comedo |
| AL-155 | Ductal comedo | |||
| BRCA1/BRCA2 carrier | 126 | 0.79% | BR-115 | Ductal comedo |
| BR-119 | Ductal comedo | |||
| Sporadic breast cancer | ||||
| Early-onset breast cancer | 214 | - | ||
| Unselected breast cancer | 604 | 0.83% | 17-S | Lobular |
| MB-181 | Ductal comedo | |||
| MB-483 | Ductal | |||
| ULL-17 | Ductal | |||
| ULL-284 | Ductal | |||
| Control population | 495 | 0.80% |